Read Functional Relevance of Tetraspanins in the Immune System

Functional Relevance of Tetraspanins in the Immune System

Carlos Cabañas

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Description:Tetraspanins are small (20-50 kDa) integral membrane proteins with four transmembrane domains that have an intrinsic propensity to associate with other membrane proteins and lipids giving rise to the formation of specific tetraspanin-enriched microdomains (TEMs), also referred to as “The tetraspanin web”. In mammals, the tetraspanin family comprises of 33 different members, with the majority of the members being abundantly expressed in almost all cell types, including leukocytes which are responsible for innate and adaptive immunity as well as in other cells that play pivotal roles in immune responses, such as endothelial or stromal cells. Therefore, through the wide range of specific molecular interactions in which they are engaged, tetraspanins influence many processes of up-most relevance in the development, physiology and pathology of the immune system, including the control of immune cell morphology, signaling, adhesion, migration, invasion, fusion, infections and cancer.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Functional Relevance of Tetraspanins in the Immune System. To get started finding Functional Relevance of Tetraspanins in the Immune System, you are right to find our website which has a comprehensive collection of manuals listed.
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Pages: 144

Format: PDF, EPUB & Kindle Edition

Publisher: Frontiers Media SA

Release: 2019

ISBN: Igg3mMpta9YC

Description: Tetraspanins are small (20-50 kDa) integral membrane proteins with four transmembrane domains that have an intrinsic propensity to associate with other membrane proteins and lipids giving rise to the formation of specific tetraspanin-enriched microdomains (TEMs), also referred to as “The tetraspanin web”. In mammals, the tetraspanin family comprises of 33 different members, with the majority of the members being abundantly expressed in almost all cell types, including leukocytes which are responsible for innate and adaptive immunity as well as in other cells that play pivotal roles in immune responses, such as endothelial or stromal cells. Therefore, through the wide range of specific molecular interactions in which they are engaged, tetraspanins influence many processes of up-most relevance in the development, physiology and pathology of the immune system, including the control of immune cell morphology, signaling, adhesion, migration, invasion, fusion, infections and cancer.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Functional Relevance of Tetraspanins in the Immune System. To get started finding Functional Relevance of Tetraspanins in the Immune System, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

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Functional Relevance of Tetraspanins in the Immune System

Functional Relevance of Tetraspanins in the Immune System

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