Description:The early steps in corticogenesis are decisive for the correct unfolding of neurogenesis, neuronal migration and differentiation under tight genetic control. In this monograph, the author outlines the main events in human preplate formation, the gradual transformation of the preplate into the cortical plate, and the establishment of the transient compartments of the foetal cortical wall. The main neuronal populations of the embryonic and foetal cortex are presented according to their timetable of appearance and the expression of developmentally relevant gene products, with the main focus on members of the Reelin-Dab1 signalling pathway, LIS1 and Doublecortin, all of which are crucial for cortical migration. The often significant developmental differences between the lissencephalic rodent brain, which has become the prevailing model of corticogenesis, and the highly differentiated, gyrated human brain are pointed out and discussed.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Advances in Anatomy, Embryology and Cell Biology, Volume 189: Genetic Control of Neuronal Migrations in Human Cortical Development. To get started finding Advances in Anatomy, Embryology and Cell Biology, Volume 189: Genetic Control of Neuronal Migrations in Human Cortical Development, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.
Pages
—
Format
PDF, EPUB & Kindle Edition
Publisher
—
Release
—
ISBN
354036689X
Advances in Anatomy, Embryology and Cell Biology, Volume 189: Genetic Control of Neuronal Migrations in Human Cortical Development
Description: The early steps in corticogenesis are decisive for the correct unfolding of neurogenesis, neuronal migration and differentiation under tight genetic control. In this monograph, the author outlines the main events in human preplate formation, the gradual transformation of the preplate into the cortical plate, and the establishment of the transient compartments of the foetal cortical wall. The main neuronal populations of the embryonic and foetal cortex are presented according to their timetable of appearance and the expression of developmentally relevant gene products, with the main focus on members of the Reelin-Dab1 signalling pathway, LIS1 and Doublecortin, all of which are crucial for cortical migration. The often significant developmental differences between the lissencephalic rodent brain, which has become the prevailing model of corticogenesis, and the highly differentiated, gyrated human brain are pointed out and discussed.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Advances in Anatomy, Embryology and Cell Biology, Volume 189: Genetic Control of Neuronal Migrations in Human Cortical Development. To get started finding Advances in Anatomy, Embryology and Cell Biology, Volume 189: Genetic Control of Neuronal Migrations in Human Cortical Development, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.