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Microbiology and Aging: Clinical Manifestations

Steven L. Percival
4.9/5 (20771 ratings)
Description:Theworld spopulationisestimatedtoreach8. 9billionby2050with370million peopleof80yearsofageorolder. Ageingisanincurablediseaseandde?nedasthe deregulationofbiochemicalprocessesimportantforlife, butforthepurposeof this book, ageing is better de?ned as the biological process of growing older. Ageingispartofnaturalhumandevelopment. Asyouwillseethroughoutthisbook, themicrobiologicalburdenonthehostis enormousandclinicallysigni?cant, andwillundoubtedlyhavearoletoplayinthe ageing process. As humans are living longer, there is a greater propensity to infection. This risk is substantially heightened in elderly individuals who are predisposedtoinfection. Whiletheprocessofageinganditseffectsonthehost s microbiology are poorly documented and researched, data obtained from gut studieshaveshownthatmicrobiologicalchangestakeplaceovertimesuggesting signi?cancetothehost. Dothemicrobiologicalchangesthatoccurwithinandupon thehostin?uencetheprocessofageingorisitthebiologicalchangesofthehost thataffectsthemicrobiology?Doesthisthereforeaffectourpropensitytodisease? Asthehost smicrobiologychangeswithageing, isthissigni?cantlybene?cialor severelydetrimentaltothehost?Aretherewaysofenhancinglifeexpectancyby reducingcertainbacteriafromproliferatingorconverselybyenhancingthesurvival ofbene?cialbacteria? Thisbookconsidersthemicrobiologyofthehostindifferentregionsofthebody andhowthesevaryinthedifferentagegroups. Chapter1ofthebookfocuseson ageingtheorieswithChap. 2consideringthehumanindigenous?oraandhowthis isaffectedduringageing. Chapter3highlightsthemaininfectionsassociatedwith anelderlypopulation, whileChap. 4reviewstheprocessofskinageingandits associatedmicrobiology. Chapter5reviewstheageinglungandChap. 6reviews in?uenzaintheelderly. Chapter7highlightsthechangesthatoccurintheoral micro?ora and host defences with advanced age with Chap. 8 reviewing the in?uenceofthegutmicrobiotawithageing. Chapter8focusesonthegutandits associatedimmunity. Theremainingfourchaptersofthebookconsiderclostridium andtheageinggut, Helicobacterpyloriandthehygienehypothesisandthebene?ts of probiotics. The microbiology theory of autism in children is reviewed in vii viii Preface Chap. 13. The?nalchapterofthebookexamineshowthebene?cialmicrobiology ofthehostleadstohumandecomposition. Thisbookencompassesacollectionofreviewsthathighlightthesigni?canceof andthecrucialrolethatmicroorganismsplayinthehumanlifecycle. Flintshire, UK StevenL. Percival Contents 1 AgeingTheories, DiseasesandMicroorganisms. . . . . . . . . . . . . . . . . . . . . . . . . 1 StevenL. Percival 2 IndigenousMicrobiotaandAssociationwiththeHost. . . . . . . . . . . . . . . . . 15 JohnG. ThomasandStevenL. Percival 3 InfectionsintheElderly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 KnutOhlsen, SvitlanaKozytska, andUdoLorenz 4 SkinAgingandMicrobiology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 LeslieBaumann, EdmundWeisberg, andStevenL. Percival 5 LungInfectionsandAging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 SameerK. MathurandKeithC. Meyer 6 In?uenzaintheElderly. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 CaterinaHatzifotiandAndrewWilliamHeath 7 ChangesinOralMicro?oraandHostDefences withAdvancedAge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131 RimondiaS. Percival 8 In?uenceoftheGutMicrobiotawithAgeing. . . . . . . . . . . . . . . . . . . . . . . . . 153 EileenMurphy, CarolineMurphy, andLiamO Mahony 9 AgingAffectsGut-AssociatedImmunity . . . . . . . . . . 175 JosephF. AlbrightandJuliaW. Albright 10 ClostridiumandTheAgeingGut. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223 SarahConnorandStevenL. Percival ix x Contents 11 TheSigni?canceofHelicobacterPyloriAcquisition andtheHygieneHypothesis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 StevenL. Percival 12 ProbioticsandtheAgeingGut. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275 StevenL. Percival 13 MicrobiologicalTheoryofAutisminChildhood . . . . . . . . . . . . . . . . . . . . . 291 StevenL. Percival 14 DecompositionofHumanRemains. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313 RobertC. Janaway, StevenL. Percival, andAndrewS. Wilson Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 335 Contributors JosephF. Albright, PhD Departmentof Microbiology, Immunology and Tropical Medicine, The George WashingtonUniversitySchoolofMedicine, Washington, DC, USA JuliaW. Albright, PhD Departmentof Microbiology, Immunology and Tropical Medicine, The George WashingtonUniversitySchoolofMedicine, Washington, DC, USA LeslieBaumann, MD U...We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Microbiology and Aging: Clinical Manifestations. To get started finding Microbiology and Aging: Clinical Manifestations, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.
Pages
Format
PDF, EPUB & Kindle Edition
Publisher
Release
ISBN
1588296407

Microbiology and Aging: Clinical Manifestations

Steven L. Percival
4.4/5 (1290744 ratings)
Description: Theworld spopulationisestimatedtoreach8. 9billionby2050with370million peopleof80yearsofageorolder. Ageingisanincurablediseaseandde?nedasthe deregulationofbiochemicalprocessesimportantforlife, butforthepurposeof this book, ageing is better de?ned as the biological process of growing older. Ageingispartofnaturalhumandevelopment. Asyouwillseethroughoutthisbook, themicrobiologicalburdenonthehostis enormousandclinicallysigni?cant, andwillundoubtedlyhavearoletoplayinthe ageing process. As humans are living longer, there is a greater propensity to infection. This risk is substantially heightened in elderly individuals who are predisposedtoinfection. Whiletheprocessofageinganditseffectsonthehost s microbiology are poorly documented and researched, data obtained from gut studieshaveshownthatmicrobiologicalchangestakeplaceovertimesuggesting signi?cancetothehost. Dothemicrobiologicalchangesthatoccurwithinandupon thehostin?uencetheprocessofageingorisitthebiologicalchangesofthehost thataffectsthemicrobiology?Doesthisthereforeaffectourpropensitytodisease? Asthehost smicrobiologychangeswithageing, isthissigni?cantlybene?cialor severelydetrimentaltothehost?Aretherewaysofenhancinglifeexpectancyby reducingcertainbacteriafromproliferatingorconverselybyenhancingthesurvival ofbene?cialbacteria? Thisbookconsidersthemicrobiologyofthehostindifferentregionsofthebody andhowthesevaryinthedifferentagegroups. Chapter1ofthebookfocuseson ageingtheorieswithChap. 2consideringthehumanindigenous?oraandhowthis isaffectedduringageing. Chapter3highlightsthemaininfectionsassociatedwith anelderlypopulation, whileChap. 4reviewstheprocessofskinageingandits associatedmicrobiology. Chapter5reviewstheageinglungandChap. 6reviews in?uenzaintheelderly. Chapter7highlightsthechangesthatoccurintheoral micro?ora and host defences with advanced age with Chap. 8 reviewing the in?uenceofthegutmicrobiotawithageing. Chapter8focusesonthegutandits associatedimmunity. Theremainingfourchaptersofthebookconsiderclostridium andtheageinggut, Helicobacterpyloriandthehygienehypothesisandthebene?ts of probiotics. The microbiology theory of autism in children is reviewed in vii viii Preface Chap. 13. The?nalchapterofthebookexamineshowthebene?cialmicrobiology ofthehostleadstohumandecomposition. Thisbookencompassesacollectionofreviewsthathighlightthesigni?canceof andthecrucialrolethatmicroorganismsplayinthehumanlifecycle. Flintshire, UK StevenL. Percival Contents 1 AgeingTheories, DiseasesandMicroorganisms. . . . . . . . . . . . . . . . . . . . . . . . . 1 StevenL. Percival 2 IndigenousMicrobiotaandAssociationwiththeHost. . . . . . . . . . . . . . . . . 15 JohnG. ThomasandStevenL. Percival 3 InfectionsintheElderly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 KnutOhlsen, SvitlanaKozytska, andUdoLorenz 4 SkinAgingandMicrobiology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 LeslieBaumann, EdmundWeisberg, andStevenL. Percival 5 LungInfectionsandAging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 SameerK. MathurandKeithC. Meyer 6 In?uenzaintheElderly. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 CaterinaHatzifotiandAndrewWilliamHeath 7 ChangesinOralMicro?oraandHostDefences withAdvancedAge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131 RimondiaS. Percival 8 In?uenceoftheGutMicrobiotawithAgeing. . . . . . . . . . . . . . . . . . . . . . . . . 153 EileenMurphy, CarolineMurphy, andLiamO Mahony 9 AgingAffectsGut-AssociatedImmunity . . . . . . . . . . 175 JosephF. AlbrightandJuliaW. Albright 10 ClostridiumandTheAgeingGut. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223 SarahConnorandStevenL. Percival ix x Contents 11 TheSigni?canceofHelicobacterPyloriAcquisition andtheHygieneHypothesis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 StevenL. Percival 12 ProbioticsandtheAgeingGut. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275 StevenL. Percival 13 MicrobiologicalTheoryofAutisminChildhood . . . . . . . . . . . . . . . . . . . . . 291 StevenL. Percival 14 DecompositionofHumanRemains. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313 RobertC. Janaway, StevenL. Percival, andAndrewS. Wilson Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 335 Contributors JosephF. Albright, PhD Departmentof Microbiology, Immunology and Tropical Medicine, The George WashingtonUniversitySchoolofMedicine, Washington, DC, USA JuliaW. Albright, PhD Departmentof Microbiology, Immunology and Tropical Medicine, The George WashingtonUniversitySchoolofMedicine, Washington, DC, USA LeslieBaumann, MD U...We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Microbiology and Aging: Clinical Manifestations. To get started finding Microbiology and Aging: Clinical Manifestations, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.
Pages
Format
PDF, EPUB & Kindle Edition
Publisher
Release
ISBN
1588296407
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